The university tweeted a statement saying: “The Biomedical Sciences building at the University of St Andrews has suffered a serious fire late this afternoon.
“No reports of any injuries or anyone in the building. The Fire Brigade are still at the scene.”
A fire service spokesman said: “More than 30 firefighters are currently tackling a well developed fire at a St Andrews University building.
“The Scottish Fire and Rescue Service was alerted at 4.58pm on Sunday, February 10 to reports of a fire involving suspected hazardous materials on North Haugh Street, St Andrews.
“Operations Control mobilised eight fire engines including a height appliance and specialist resources.
“Firefighters are currently tackling the flames.”