Scientists develop molecule that attacks natural defences of superbugs

Scientists develop molecule that attacks natural defences of superbugs

“When used at normal levels colistin is potentially toxic but we have shown that when used in conjunction with our compound you can reduce the amount of antibiotic required by about 16 times,” he said.
This is a “proof of concept” study and has yet to be tested in humans. The next step is to determine whether other bacteria could be targeted by the compound. 
“What’s unique about our study is that all bacteria have a communication system and different families of bacteria have different languages. The communication system we looked at is much less well studied than others,” said Dr O’Sullivan. 
He added: “As more microbes develop resistance to current antibiotics, and relatively few new antibiotics are coming to market, we need to identify new ways of dealing with resistant infections. The approach outlined in our work has significant potential.”
Dr Pol Huedo, co-author of the study, said the findings “validate the strategy of interfering with bacterial communication to combat difficult-to-treat infections caused by resistant organisms”.
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